Fun fact: the dates on these mean nothing except the order of events. Unless it's actually in the later stages like when humanity is strutting around in space and exact dates are necessary due to the many events being more crammed together, it's probably just a number put their for estimation and it doesn't matter that much anyway since the general gist is "plants weren't even on land yet at this point".
Having processed the alien cult into edibles and made countless subspecies of themselves to survive on other planets, the Old Ones found themselves having quite the taste for the blood of xeno scum and enforcing an ideology in relation to anything they believed to pose a potential threat to the Old Ones that went a little like this:
"Hippitty hoppitty your heart will now stoppitty."
Loki was a means to this stoppitty end.