Drakenphage

Llewellyn's Icthyodrome

---

Caused by a genetic mutation engendered by proximal dragonborn genetics in the FLG, or filligrin gene, this

atopic disease is characterised by xerosis, ultralinear palm and plantar surfaces, and ovalar keratoses strongly resembling nothing so much as fish or dragon scales. In most cases, these kerotoses are waxy and while incurable without magical means, are easily treatable with ready made unguents and ointments. People live long, healthy lives if they can avoid too many diseases of the skin, which they will have a hard time fighting off without medical intervention.
In very rare cases, the kerotoses develop into chitinous, overlapping scales that offer a modicum of protection to the so afflicted. The stricken will rarely be sunburnt, for instance, and in extremely rare cases, some people's growths can even turn aside a blade.

Transmission & Vectors

It is impossible to "catch" the phage from another person, even if they have it and are shedding scales into your soup. It can, however, be acquired by filligrin deficient people who come into contact with specific fungi and bacterium. Their body's fight to heal itself misfires, and the kerotoses begin to appear. This disease can then be passed on to future generations.

Causes

A loss-of-function mutation in FLG5.

Symptoms

Scaley and rough skin that resembles fish, or dragon, scales.
The afflicted also becomes immune to poisons and foodborne illnesses; which is a boon, yes, but also a curse, as potions and oral medications no longer have any effect.

Treatment

(There are many treatments, but they all contain a weak petroleum kerosene, which seems to help in the vast number of cases)

Prognosis

Long, healthy lives, if properly vigilant and lucky.

Sequela

As the skin of the victim ages, it becomes easier and easier to infect, and the afflicted must choose between the safety of a clean home and the insecurity of time away.

Affected Groups

Humans, Elves, and Gnomes seem to be the only affected species on Tellus.

Hosts & Carriers

The scales can vary in color, size, and thickness, and often form interesting patterns on afflicted patches of skin.

Prevention

Avoiding communicable fungi is a great first step. For more information, contact the Tellusian General Hospital in Craysilt, run by the The Siblings of the White Cross:
Craysilt General Hosp. Paradermatology Dpt. Attn: Dr. Haskell Southbay 6120-405

Epidemiology

One must first have the loss-of-function mutation in FLG5, and then come in contact with the pathogens. However, its ability to alter ribonucleic sequences make it a formidable disease.
It is, by far, most prevalent in the Rhegev Desert area of Taisha. It is hypothesized that whatever radiation caused the formation of the Sea of Glass caused the LOF mutation on FLG5.

History

Affecting less than a tenth of one percent of the population of Tellus, there is not much in the annals of history about this affliction in particular, but there are so many myths, stories, and fairy tales surrounding it that many in the science field will not study it.

Cultural Reception

The so afflcited are utterly shunned by a society ruled by prejudice and ignorance, and in many cases develop maladaptive coping mechanisms that cause no end of trouble.

14 Juno, 5438NG

Parabiology 411

Prof. Haskell

Rare Genetic Mutations

End-of-Term Paper

Type

Genetic

Origin

Mutated

Cycle

Chronic, Acquired & Congenital

Rarity

Extremely Rare

Affected Species

• Human
• Elves
• Gnomish