The major sentient populator of the The United States of America, Humans are intelligent and adaptable, though prone to illness and with naturally short lifespans. Humans while, the dominant species, could also be considered a type of "progenitor race" as most other sentient species Post-War originated from Humans. Such subspecies include:
- Super Mutants
- Generation 3 Synths NOTE: Despite being artificially created, Gen3 synths *are* organic beings and *can* naturally reproduce under the correct circumstances. See the related article for more details.
- Pure or Prime Humans
- Rad-Im Humans
- Ghost People