Hemathropism

Hemathropism is a rare genetic condition found among some inhabitants of the Fortrop, characterised by blood that is significantly darker and thicker than that of a typical human. It's caused by a mutation in the genes responsible for hemoglobin production, leading to the formation of an altered hemoglobin variant called "hemathropin."

Transmission & Vectors

Hemathropism is primarily genetic and inherited in an autosomal recessive manner

Causes

Hemathropism is primarily caused by a specific mutation in the HBB gene, which is responsible for producing the beta-globin subunit of hemoglobin. This mutation alters the normal structure and function of hemoglobin, leading to the creation of a variant known as hemathropin.

The mutation follows an autosomal recessive inheritance pattern. This means that for a child to be born with Hemathropism, both parents must carry at least one copy of the mutated gene. If both parents are carriers, there is a 25% chance with each pregnancy that their child will inherit two copies of the mutation, resulting in Hemathropism.

Living in a space environment with lower oxygen levels have provided an evolutionary advantage for individuals with the hemathropism mutation, allowing them to adapt better to their surroundings. Over time, this selective pressure might have made it more common among the population.

Symptoms

1. The blood of individuals with hemathropism is a deep, almost black hue, due to the high concentration of hemathropin;
2. Increased blood viscosity (and so, hypertension
3. While hemathropin is designed to enhance oxygen affinity, the thicker blood hinders effective blood flow, leading to fatigue and weakness due to less efficient oxygen delivery to tissues;
4. Increased resting heart rate;
5. Headaches, dizziness, or lightheadedness;
6. Difficulties with temperature regulation.

Treatment

Currently, there are no definitive treatments available for Hemathropism due to its congenital nature and genetic basis. Management of the condition primarily focuses on alleviating symptoms and preventing complications rather than curing the underlying genetic mutation

Prognosis

The prognosis for individuals with Hemathropism varies based on the severity of the symptoms and the effectiveness of management strategies. Individuals with mild symptoms lead relatively normal lives, whereas those with more severe complications face ongoing health complications (i.e. hypertension, blood clots, organ stress)

Sequela

Pathological Conditions:

1. High Blood Pressure (Hypertension
2. Blood clots;
3. Organ damage;
4. Chronic fatigue;

They can, potentially, develop into:

1. Heart failure;
2. Kidney disease;
3. Stroke;
4. Pulmonary complications.

History

A child named Zoe Talon was the first recorded case of Hemathropism. Born to parents who were both descendants of the original test subjects, Iris displayed the condition’s unique characteristics from a young age.

While this case marked the start of documented instances of Hemathropism, the condition was largely ignored in public discourse. The scientific community treated it as an isolated anomaly, continuing their research without public scrutiny.

As additional cases of Hemathropism began to surface, they remained confined to elite medical circles. The phenomenon was labeled under other diseases to avoid alarming the general population. Medical professionals involved in the initial studies attributed the dark blood to conditions such as porphyria or hemolytic anemia, effectively covering up the truth and keeping Hemathropism out of the public eye.

Cultural Reception

There is a lot of scepticism around Hemathropism. Being as rare as it is, not many people know about it, especially not with the limited medical knowledge on it being locked away to the elite. So, while the general populace lacks detailed knowledge about the condition, they are aware enough to form opinions influenced by misinformation.

In the lower classes, individuals with Hemathropism are often seen as objects of fear and suspicion. Many believe that the dark blood indicates toxicity or poison, associating it with dangerous diseases. People often dismiss the Hemathropes as "tainted".

In the middle classes, views on Hemathropism are mixed. Some hold onto the superstitions that circulate in the lower classes, perceiving Hemathropes as cursed or marked by fate. Others see them as merely different. While there may be an element of curiosity about those with the condition, this curiosity is often coupled with skepticism. Many wonder how beneficial a trait like "black blood" can truly be, questioning whether such individuals can be trusted or should be respected.

Among the elite, the reception of Hemathropism is particularly harsh. This class is known for its emphasis on conformity and appearances, leading to strong disdain for anything that deviates from societal norms. The existence of Hemathropes is often met with outright contempt and revulsion. The upper classes are quick to dismiss affected individuals, labelling them as inferior or suspect. Although some within this group may be privy to the scientific research surrounding Hemathropism, most prefer to ignore its existence, viewing it as a blemish within their group.

Type

Genetic

Origin

Engineered

Cycle

Chronic, Congenital

Rarity

Extremely Rare

Affected Species

• Human