Hayflick limit advanced by American Leonard Hayflick. This is the number of times a cell can divide before it can do so no longer.
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Project Daedalus Timeline
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1962 CE
Hayflick Limit
Discovery, Scientific -
1971 CE
First Identification of Telomeres
Discovery, ScientificRussian theorist Alexey Olovnikov first recognised that chromosomes could not completely replicate their ends
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1975 CE
First Description of Telomeres
Discovery, Scientific -
1984 CE
Discovery of Telomerase
Discovery, ScientificCarol W. Greider and Elizabeth Blackburn discover Telomerase in the ciliate Tetrahymena.
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2009 CE
Nobel Prize for Telomeres and Telomerase
Discovery, ScientificElizabeth Blackburn, Carol Greider, and Jack Szostak were awarded the Nobel Prize in Physiology or Medicine for the discovery of telomeres and telomerase
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2016 CE
Break-induced telomere synthesis underlies alternative telomere maintenance
Discovery, ScientificRobert L. Dilley, Priyanka Verma, Nam Woo Cho, Harrison D. Winters, Anne R. Wondisford, Roger A. Greenberg at University of Pennsylvania
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2017 CE
Point of Divergence
Era beginning/end -
2017 CE
5
Break-induced telomere synthesis usurped by telomerase in MCF-7
Discovery, ScientificAuthors:
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2024 CE
ISS Sold to Virgin Galactic
Construction beginning/endNASA international space station budget at end, bought by Virgin Galactic for tourism.
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2024 CE
The Fountain of Youth: telomerase modification grants immortality to cells via break induced telomere synthesis
Discovery, ScientificStephanie R. Bailey, Robert L. Dilley, Catherine Weis, Nam Woo Cho, Johann Anderson, Roger A. Greenberg.
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2029 CE
NASA establishes permanent moon station
Scientific achievement -
2031 CE
CNSA lands on Mars
Scientific achievement -
2032 CE
Geron Corp US announces Gerontib with completed phase 3 trials
Discovery, ScientificGeron originally investigated telomerase as a means of understanding and modifying human aging. However, Geron announced it ceased aging research of any kind in 2010. From 2024 until 2032, Geron was secretly working on their formula "Gerontib", under complete secrecy as ordered by US government. The data for phase 1 and 2 trials seems too good to be true, and patients went missing after treatment. Geron Biotech
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2032 CE
A phase 1 clinical trial of FK6310661: first time in patients ascending dose study
Discovery, ScientificShunsuke Kagawa, Yoshikatsu Endo, Masayoshi Hioki, Nara Kenmochi, Ryo Sakai, Yasuo Urata, Toshiyoshi Fujiwara
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2033 CE
Gerontib licensed in US, EU, China, and India under immense public pressure
Discovery, ScientificThe license and patent for Gerontib are granted in perpetuity in the US due to secretive dealings with several successive governments.
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2033 CE
UNSA/CNSA permanent international station on Mars
Scientific achievement -
2036 CE
Gerontib begins to be produced illegally on the blackmarket
Discovery, Scientific -
2039 CE
UNSA/CNSA Mars station is destroyed
Disaster / Destruction -
2041 CE
Astellas Pharma releases Teromerin
Discovery, ScientificAn independently discovered telomerase modifying drug that produces similar effects to Gerontib. The growing class of drugs are called Telmods (first generation). Astellas Pharma Inc.
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2045 CE
UNSA module added to NASA moon station
Scientific achievement -
2046 CE
Sanofi release Vitahib
Discovery, ScientificA first generation Telmod.
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2050 CE
Sea Levels Have Risen 1m Due to Global Warming
Geological / environmental eventCountries most affected: Netherlands, Poland, Portugal, Tunisia, Italy, Israel, Palestine, Mauritania, Togo, Benin, Djibouti, Iraq, Bahrain, Bangladesh, Vietnam, Pacific Islands, Suriname, Guyana.
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2054 CE
International Mars station established
Scientific achievementUNSA, CNSA, NASA, and Roscosmos international station.
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2060 CE
Population of earth 10 billion
Life, BirthPopulation is 1 billion greater than expected pre-telomerase modification. Three billion live on breadline, rioting is common, governments rise and fall
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2064 CE
Russia invades Turkmenistan
Military actionRussian boots enter Turkmenistan via Russian Kazakhstan. China answers the calls for defence with its own military forces. After months of fighting with high casualties on both sides, Chinese ally Pakistan attempts launch of tactical nuclear device. The device is shot down by Russian countermeasures.
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2064 CE
10
Nuclear Winter of 2064-2074
Disaster / DestructionCaused by the nuclear armament launched by Pakistan and destroyed mid-air by Russian countermeasures. Billions starve, are driven out of their home by war and revolution, and freeze.
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2065 CE
2
St. Helena Conference
Diplomatic actionWorld leaders meet and a truce is established between China and Russia. Neutral US and EU countries act as mediators. No highly profitable land is transferred to either nation. Turkmenistan is framed as an aggressor towards Russia, and Pakistan is blamed for its unprovoked nuclear assault that China was "unaware of".
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2065 CE
11
TAW established
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2065 CE
11
Hiroshima Conference
Diplomatic actionA peace treaty signed between Pakistan, Turkmenistan, Russia, and China. The issue of overpopulation is agreed to be solved by further space colonization. All parties agree to launch spacecraft under the law and government of a new body, the TAW.
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2068 CE
Scale colonisation of Mars begins
Population Migration / TravelAs agreed on at the Hiroshima Conference, Earth powers sent their overburdening populations to Mars under the supervision of the TAW.
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2089 CE
24 /12
Crash of TAW Calypso
Population Migration / Travel
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