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Zeta-strain Toxoplasmosis

This is the infection with a very aggressive mutated strain of Toxoplasma gondii. After a incubation period of 3hrs to 20 days the human host of this parasite will start to develop symptoms such as confusion and aggression as well as non-tender swelling of the lymphatic system and loss of visual acuity. over the course of the next week the host's condition will progress until the host displays no social responses and seemingly exists to hunt and feed on uninfected, thus enabling the spread of the parasite.  

Stages of Zeta-Strain-Toxoplasmosis

toxoplasmosis progresses through several stages   Gestation (0 - 20 days)
Toxoplasma oocytes attach themselves to the walls of the digestive system and develop into first phase. This phase is skipped if the host encounters Mature Bradyzoites.
  Inflammation (6 - 72 hours)
Mature bradyocites begin to asexually multiply, releasing oocytes that travel through the blood stream to the brain, liver, kidneys and eyes. This triggers an immune response from the host who experiences symptoms including, but not limited to:
  • Fatigue
  • Irritability
  • Paranoia
  • Headaches
  • Swelling of lymph nodes
  • Itching eyes
Up until the end of this stage the disease is treatable and complete recovery possible, though host are not likely to seek out medical assistance.

Delirium / aggression (3 - 14 days)
Surviving Oocites damage tissues in the host as they multiply. This involves damage to the frontal cortex, eyes, lymphatic system etc. This causes the following symptoms on top of previous symptoms:
  • Confusion
  • Loss of inhibitions
  • Aggression
  • Loss of visual acuity
  • Hunger
This damage is unrecoverable, though further damage can be avoided with swift treatment with .

Brain death (Terminal)
At this stage the host's brain function is diminished to the same level as a koala. Able to identify moving and loud objects as food and to attack them, but not much more. Their vision is usually greatly impaired at this point. The disease does not progress past this point and the host can live as long as it isn't killed by exposure, injury or starvation/dehydration.

Treatment

Combination Vancomycin and Zosyn is the most effective at treating zeta Strain toxoplasmosis but has a slew of dangerous side effects IV 600mg every 6 hours for 2 days This is an extremely dangerous procedure, risking internal hemorrhaging, kidney failure and heart failure. Patient will also suffer Pain, swelling, diarrhea, fever, delirium.    pyrimethamine-sulphadiazine  2 grams twice Daily for 1 month   Azithromycin   600mg thrice daily for 1 month   Doxycycline 200mg thrice daily for 1 month   Not enough studies on trimethoprim-sulfamethoxazole (TMP-SMX) or pyrimethamine plus clindamycin plus folinic acid have been done to prove their effectiveness and safety enough to be recommended. However, if the pyrimethamine, sulfadiazine, and folinic acid regimen is in short supply or cannot be administered to the patient, these alternative regimens theoretically could be used.
Type
Parasitic
Origin
Natural
Cycle
Chronic, Acquired & Congenital
Rarity
Common
Transmission of Zeta-Strain-Toxoplasma Gondii
Zeta-Strain-Toxoplasma Gondii can be contracted and transmitted through several vectors:
  • consumption of undercooked infected meat
  • Consumption of contaminated produce
  • Contact with infected feline fecal mater
  • Sub-dermal contact with infected blood or lymph fluid

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