Cybernetics

Naturally, regen treatments can't replace lost limbs, but cloning technology is there to pick up the slack. When that's not an option, life-like prosthetics are usually available, but there's little reason to prefer them, since they don't exactly grant superpowers.
To communicate, people still use various mobile devices, either hand-held, wrist worn, goggle-shaped, or more exotic options. Some go as far as using medical nanobots to reshape part of their jawbone into a voice activated comm implant. (Cyborgs, of course, don't need one, and Sorcerers can't have one -- see Transhumans.)
Computing power is such that many computer enthusiasts can acquire the hardware required to run a mind upload. The latter, of course, are a lot harder to get by, and true artificial intelligences even more so. But ordinary software is powerful enough to let humanoid robots perform low-end jobs such as bartender or receptionist.

What about AI and mind uploads?

Mind upload is possible, but the procedure is often imperfect, and mind download is only speculative. As for artificial intelligence... it's a crapshoot. No known technique can produce true AIs reliably, so they're rare.