CASandra
CASandra is one of the first "wonder drugs" of genetic engineering to be developed. It uses CRISPR/CAS9 technology insert a gene into patients to make a protein that makes blood transfusions universal. The protein in question works by destroying the H-antigen, meaning that essentially everybody with the treatment has the Bombay blood group. People with this blood type can donate to anybody.
Once the blood donation is finished, they are given a second drug that acts as an "off switch," immediately causing CASandra and related enzymes to denature. Without this off switch CASandra stops working after about two weeks anyway. This was implemented as a safety feature, given the fact this is technically a gene therapy.
CASandra, in spite of being a gene therapy, is less expensive over time than Hemocleave because it is public domain. This decision was made after the head researcher's daughter, Casandra, died due to the lack of available Type O negative blood after she was in a car accident in spite of Hemocleave being on the market. Casandra is also where the drug gets its name, in addition to being derived from CAS9 technology.
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