Rem Alternis Shadowrun
In 2080 Denver is still a separated city. In some places, when you cross the street, you cross the borders of two countries. All those different jurisdictions mean a lot of opportunities for Shadowrunners.
Your PCs are new to the city, refugees from a run gone bad that burned their previous identities.
Another more experienced Shadowrun crew hired you to be part of their job, and you didn't know anything beyond your part of the job. However, the nuyen was on target, and your tasks were well laid out, so you took the job.
Player knowledge: This was a huge multi-city Shadowrun run with multiple levels of teams.
You got the first half of the run done and were in the required holding pattern when the commlink you were using for the run went nuts, being filled with AR spam to the point of being useless. At this point, the commlink in the survival bag given to you as part of the run sent an urgent message. You open the message and see the face that hired you speaking into it. She is taking cover while under fire. "The run's blown, everything compromised. Pull out and go to ground burn your sins", as she turns to lay down some cover fire, the message closes in a burst of static.
Looking around, you spot someone paying the wrong kind of attention to you and decide to bolt. After taking and returning heavy fire, you do manage to make it out of town. However, you end up limping into Denver.
Your identity burned you spend the last of your accessible nuyen on a new SIN in Denver. After that, you eke out an existence on the fringe of the Denver Shadows, trying to earn enough rep to get a real Shadowrun.