The Black Death entered Genoa and Venice

Plague / Epidemic

A group of Ryukishi board a fleet of Genovese trading ships that are fleeing the city of Caffa.  The inflect the cargo and kill the crew, so that by the time the ship arrives Messina, Italy, they were all dead or dying.  The local population looted the ships and carried the plagued and cursed items home.  The dark gentry of Messina joined in Shilin Won’s plan.   By the end of 1347, so did the nobles of Genoa and Venice joined as well.